Search on: HEAVY CHAIN DISEASE, IGA TYPE 
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Descriptor English:   Immunoproliferative Small Intestinal Disease 
Descriptor Spanish:   Enfermedad Inmunoproliferativa del Intestino Delgado 
Descriptor Portuguese:   Doença Imunoproliferativa do Intestino Delgado 
Synonyms English:   alpha-Chain Disease
Heavy Chain Disease, IgA Type
IPSID
Lymphoma, Mediterranean  
Tree Number:   C04.557.386.390
C06.301.371.411.512
C06.405.249.411.512
C06.405.469.491.505
C15.378.147.780.490.512
C15.604.515.435.512
C20.683.515.512
C20.683.780.490.512
Definition English:   A condition that is caused by HYPERPLASIA of LYMPHOCYTES in the small intestine (INTESTINE, SMALL) and the mesenteric LYMPH NODES. These lymphocytes produce an anomalous alpha heavy chain protein. Generally, these IPSID patients have either concurrent LYMPHOMA or develop lymphoma within a few years. The disease was first described in the Mediterranean region and is characterized by malabsorption; WEIGHT LOSS; DIARRHEA; and STEATORRHEA. 
History Note English:   87 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   19205 
Unique Identifier:   D007161 

Occurrence in VHL:
 

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